Health Encyclopedia

Tensilon test

Definition

The Tensilon test is a method to help diagnose myasthenia gravis.

How the test is performed

The drug Tensilon is slowly given through an intravenous line. The health care provider may want to fatigue your muscles by having you do various exercises such as counting until your voice diminishes or holding your arms above your shoulders until they drop. The rest of the Tensilon is then given.

You will be asked to perform some repetitive muscular movements like crossing and uncrossing your legs with particular attention paid to whether your muscle strength is improved by the Tensilon.

The test may be repeated and additional Tensilon may be given to help tell the difference between myasthenia gravis and other conditions.

How to prepare for the test

No special preparation is usually necessary. However, you should follow any dietary restrictions or other directions prescribed by your health care provider.

How the test will feel

There will be a sharp prick as the IV needle is inserted. There may be some side effects from the drug.

Why the test is performed

The test helps diagnosis myasthenia gravis, may aid in telling the difference between myasthenic and other similar neurological conditions, and may be used to monitor oral anticholinesterase therapy.

What abnormal results mean

In myasthenia gravis, the muscles will improve immediately following the Tensilon. The maximum benefit only lasts several minutes.

In myasthenic crisis (worsening of the disease that requires anticholinesterase therapy), there is a brief improvement in the muscle strength.

In cholinergic crisis (overdose of anticholinesterase), Tensilon will exaggerate the muscle weakness.

Additional conditions under which the test may be performed include Lambert-Eaton syndrome.

What the risks are

The risks are side effects from the drug, including respiratory failure.

Review Date:1/22/2007
Reviewed By:Benjamin W. Van Voorhees, MD, MPH, Assistant Professor of Medicine and Pediatrics, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.

ADAM Quality A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is the first of its kind, requiring compliance with 53 standards of quality and accountability, verified by independent audit. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial process. A.D.A.M. is also a founding member of Hi-Ethics (www.hiethics.com) and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).

The Agency for Health Care Administration (Agency) and this website do not claim the information on, or referred to by, this site is error free. This site may include links to websites of other government agencies or private groups. Our Agency and this website do not control such sites and are not responsible for their content. Reference to or links to any other group, product, service, or information does not mean our Agency or this website approves of that group, product, service, or information.

Additionally, while health information provided through this website may be a valuable resource for the public, it is not designed to offer medical advice. Talk with your doctor about medical care questions you may have.