Health Encyclopedia

Corneal transplant

Definition

A corneal transplant is surgery to replace the clear surface on the front of the eye (the cornea).

Alternative Names

Keratoplasty; Penetrating keratoplasty

Description

Most corneal transplants are done while you are awake. The health care provider will inject medicine into the eye area so you do not feel any pain during surgery. You may be given a sedative to reduce anxiety.

The tissue for the corneal transplant is taken from a recently dead person whose family agreed to donate it.

The most common type of corneal transplant is called penetrating keratoplasty. During this procedure, the surgeon removes a small circle-sized piece of your cornea. The donated cornea is stitched onto the opening in your eye. Your doctor will remove the stitches at a follow-up visit.

Indications

Corneal transplantation is recommended for persons who have:

Thinning of the cornea that causes vision problems (keratoconus)
Scarring of the cornea from severe infections or injuries
Cloudiness of the cornea that causes vision loss (Fuchs dystrophy)

Risks

Sometimes, the body rejects the transplanted tissue. This occurs in a small number of patients.

Other risks for a corneal transplant include:

Bleeding
Infection of the eye
Glaucoma
Swelling of the front of the eye

The risks for any anesthesia are:

Reactions to medications
Breathing problems

The risks for any surgery are:

Bleeding, but this is a rare complication since the cornea normally has no blood vessels
Infection

Expectations after surgery

Full visual recovery may take up to 1 year. Most patients with successful corneal transplants will enjoy good vision for many years.

Call your doctor if you have any of the following symptoms. They may be signs of a complication.

Decreased vision
Flashes of light or floaters in the eye
Light sensitivity
Redness of the eye that gets worse
Pain

Convalescence

Your doctor will give you an eye patch to wear for a short period of time. This protects the new cornea from injury.

Carefully follow your doctor's instructions regarding eye drops after surgery, which may prevent rejection.

References

Yanoff M, Duker JS, Augsburger JJ, et al. Ophthalmology. 2nd ed. St. Louis, Mo: Mosby; 2004:204-209.

Mian S. Regulation of eye banking and uses of ocular tissue for transplantation. Clin Lab Med. Sept 2005; 25(3): 607-24.

Review Date:8/22/2008
Reviewed By:Paul B. Griggs, MD, Department of Ophthalmology, Virginia Mason Medical Center, Seattle, WA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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